PREPARATION AND INVITRO EVALUATION OF SALBUTAMOL SULFATE MICROCAPSULES

被引：3

作者：

DHARAMADHIKARI, NB ^{[1
]}

JOSHI, SB ^{[1
]}

MANEKAR, NC ^{[1
]}

机构：

[1] DEPT PHARMACEUT SCI,NAGPUR UNIV CAMPUS,NAGPUR 440010,INDIA

来源：

JOURNAL OF MICROENCAPSULATION | 1991年 / 8卷 / 04期

关键词：

D O I：

10.3109/02652049109021871

中图分类号：

O69 [应用化学];

学科分类号：

081704 [应用化学];

摘要：

Microcapsules of salbutamol sulphate were prepared using cellulose acetate phthalate as a coating material and by the coacervation phase separation (solvent evaporation) technique for obtaining sustained action. Prepared microcapsules were evaluated for their drug content, physical properties, release characteristics and stability. The effect of coat to core ratio on release pattern was studied and it was found that microcapsules prepared with coat to core ratio 2:1 were able to retard the release of drug for 12 hours. No significant change was observed in drug content and release pattern even after storage.

引用

页码：479 / 482

页数：4