THERAPEUTIC HUMAN-ANTIBODIES DERIVED FROM PCR AMPLIFICATION OF B-CELL VARIABLE REGIONS

被引：20

作者：

LARRICK, JW

WALLACE, EF

COLOMA, MJ

BRUDERER, U

LANG, AB

FRY, KE

机构：

[1] GENELABS INC,REDWOOD CITY,CA 94063

[2] SWISS SERUM & VACCINE INST,BERN,SWITZERLAND

来源：

IMMUNOLOGICAL REVIEWS | 1992年 / 130卷

关键词：

D O I：

10.1111/j.1600-065X.1992.tb01521.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：69 / 85

页数：17

共 39 条

[1]

AYALA M, 1990, BIOTECHNOLOGIA APPLI, V7, P3

[2] HUMAN MONOCLONAL-ANTIBODIES PRODUCED BY PRIMARY INVITRO IMMUNIZATION OF PERIPHERAL-BLOOD LYMPHOCYTES [J].

BORREBAECK, CAK ;

DANIELSSON, L ;

MOLLER, SA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (11) :3995-3999

[3] HEAVY-CHAIN VARIABLE REGION CONTRIBUTION TO THE NPB FAMILY OF ANTIBODIES - SOMATIC MUTATION EVIDENT IN A GAMMA-2A VARIABLE REGION [J].

BOTHWELL, ALM ;

PASKIND, M ;

RETH, M ;

IMANISHIKARI, T ;

RAJEWSKY, K ;

BALTIMORE, D .

CELL, 1981, 24 (03) :625-637

[4] ANALYSES OF AFFINITY DISTRIBUTIONS WITHIN POLYCLONAL POPULATIONS OF ANTIGEN-SPECIFIC ANTIBODIES - EVALUATION OF THEIR ACCURACY IN POPULATION DETECTION USING MONOCLONAL-ANTIBODIES [J].

BRUDERER, U ;

DEUSINGER, M ;

SCHURCH, U ;

LANG, AB .

JOURNAL OF IMMUNOLOGICAL METHODS, 1992, 151 (1-2) :157-164

[5] QUALITATIVE-ANALYSIS OF ANTIBODY-BINDING - AN INVITRO ASSAY FOR THE EVALUATION AND DEVELOPMENT OF VACCINES [J].

BRUDERER, U ;

FURER, E ;

CRYZ, SJ ;

LANG, AB .

JOURNAL OF IMMUNOLOGICAL METHODS, 1990, 133 (02) :263-268

[6]

CHANG WTH, 1989, TRENDS BIOTECHNOL, V7, P360

[7] CLUSTERING OF EXTENSIVE SOMATIC MUTATIONS IN THE VARIABLE REGION OF AN IMMUNOGLOBULIN HEAVY-CHAIN GENE FROM A HUMAN B-CELL LYMPHOMA [J].

CLEARY, ML ;

MEEKER, TC ;

LEVY, S ;

LEE, E ;

TRELA, M ;

SKLAR, J ;

LEVY, R .

CELL, 1986, 44 (01) :97-106

[8]

COLOMA MJ, 1991, BIOTECHNIQUES, V11, P152

[9]

COLOMA MJ, 1990, INTERFERON BIOTECHNO, V7, P1

[10] THE PRESUMPTIVE CDR3 REGIONS OF BOTH T-CELL RECEPTOR ALPHA-CHAIN AND BETA-CHAIN DETERMINE T-CELL SPECIFICITY FOR MYOGLOBIN PEPTIDES [J].

DANSKA, JS ;

LIVINGSTONE, AM ;

PARAGAS, V ;

ISHIHARA, T ;

FATHMAN, CG .

JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 172 (01) :27-33

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