TRANSLOCATION-(2-3)(P22-Q28) IS ASSOCIATED WITH MYELOID-DISORDERS

被引：6

作者：

BERGER, R

FLEXOR, M

LECONIAT, M

DERRE, J

LEBLANC, T

机构：

[1] INST GENET MOLEC,CNRS,SDI 159541,F-75010 PARIS,FRANCE

[2] HOP ST LOUIS,PARIS,FRANCE

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 79卷 / 02期

关键词：

D O I：

10.1016/0165-4608(94)00130-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chromosome studies carried out in two children with acute myeloblastic leukemia (AML, M2) showed a t(2;3)(p22;q28). This abnormality was associated with monosomy 7 and del(12)(p12) in the first patient and was found only in relapse in the second patient. Comparison with the other previously published t(2;3) suggests that this translocation is a nonrandom abnormality involving a pluripotent stem cell and occurring as a secondary chromosome abnormality in AML.

引用

页码：130 / 132

页数：3

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