THE PREPARATION OF ALPHA-TETRALONES FROM BENZOCYCLOBUTENONES VIA SEQUENTIAL THERMAL ELECTROCYCLIC REACTIONS

被引：25

作者：

HICKMAN, DN

WALLACE, TW

WARDLEWORTH, JM

机构：

[1] UNIV SALFORD,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCS,ENGLAND

[2] ICI PHARMACEUT PLC,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)74896-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Alkenylbenzocyclobuten-1-ols, prepared from benzocyclobutenones via the addition of alkenylmagnesium bromides, or the addition of alkynyllithium reagents followed by (E)-selective reduction of the triple bond, undergo successive thermal 4-pi and 6-pi electrocyclic reactions leading to substituted 3,4-dihydro-1(2H)-naphthalenones.

引用

页码：819 / 822

页数：4

共 28 条

[1]

Arcamone F., 1981, DOXORUBICIN

[2]

ARNOLD BJ, 1974, J CHEM SOC PERK T 1, P415, DOI 10.1039/p19740000415

[3] 3,6-DIMETHOXYBENZOCYCLOBUTENONE - A REAGENT FOR QUINONE SYNTHESIS [J].