GENOTOXICITY OF POLYCYCLIC AROMATIC-HYDROCARBONS IN ESCHERICHIA-COLI PQ37

被引：95

作者：

MERSCHSUNDERMANN, V

MOCHAYEDI, S

KEVEKORDES, S

机构：

来源：

MUTATION RESEARCH | 1992年 / 278卷 / 01期

关键词：

SOS CHROMOTEST; POLYCYCLIC AROMATIC HYDROCARBONS; GENOTOXICITY;

D O I：

10.1016/0165-1218(92)90279-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In the present investigation, 32 polycyclic aromatic hydrocarbons (PAHs) were tested for genotoxicity in E. coli PQ37 using the standard tube assay of the SOS chromotest. PAHs such as benzo[ghi]fluoranthene, benzo[j]fluoranthene, benzo[a]pyrene, chrysene, dibenzo[a,l]pyrene, fluoranthene and triphenylene exhibited high genotoxicity when incubated in the presence of an exogenous metabolic activation mixture. The results were compared to those obtained with the Salmonella/microsome test.

引用

页码：1 / 9

页数：9

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