AMINOLYSIS OF N-ACYLPYRAZOLES

被引：33

作者：

KASHIMA, C

FUKUCHI, I

TAKAHASHI, K

HOSOMI, A

机构：

[1] Department of Chemistry, University of Tsukuba, Tsukuba, Ibaraki

来源：

HETEROCYCLES | 1994年 / 38卷 / 06期

关键词：

D O I：

10.3987/COM-94-6711

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Acylpyrazoles reacted with amines having a tiny substituent to afford the corresponding amides. The aminolysis with bulky amines was controlled to be retarded by the steric factors. Due to this steric interaction, the stereoselective aminolysis was observed. This selectivity of aminolysis should increase the utility of pyrazoles as auxiliary compounds in the synthetic loop.

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页码：1407 / 1412

页数：6

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