URINARY N-ACETYL-BETA-D-GLUCOSAMINIDASE IN THE PREDICTION OF PREECLAMPSIA AND PREGNANCY-INDUCED HYPERTENSION

被引：9

作者：

JACOB, M

WILFRED, G

KANAGASABAPATHY, AS

BALASUBRAMANIAM, N

机构：

[1] Christian Medical College, Vellore

来源：

AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY | 1993年 / 33卷 / 04期

关键词：

D O I：

10.1111/j.1479-828X.1993.tb02119.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Urinary N-acetyl-beta-D-glucosaminidase was estimated in 109 primigravidas and the level correlated with the subsequent development of preeclampsia and pregnancy-induced hypertension in these women. The enzyme value was significantly higher in those who developed preeclampsia. Its sensitivity and specificity for the prediction of the disorder were 80% and 78% respectively. The positive predictive value was 21% while the negative predictive value was 98%.

引用

页码：395 / 397

页数：3

共 7 条

[1]

O'Brien WF, Predicting Pre‐eclampsia, Obstet Gynecol, 75, pp. 445-449, (1990)

[2]

Goren MP, Sibai BM, El-Nazar A., Increased tubular enzyme excretion in preeclampsia, Am J Obstet Gynecol, 157, pp. 906-908, (1987)

[3]

Wellwood JM, Price RG, Ellis BG, Thomson AE, A note on the practical aspects of the assay of N‐acetyl‐β‐D‐glucosaminidase in human urine, Clin Chim Acta, 69, pp. 85-91, (1976)

[4]

Chun-Ting, Price RG, Chattagoon L, Richardson AC, Percy FG, Colorimetric assays for N‐acetyl‐β‐Dglucosaminidase & β‐D‐galactosidase in human urine using newly developed W‐nitrostyryl substrates, Clin Chim Acta, 124, pp. 195-204, (1982)

[5]

Cunningham FG, Macdonald PC, Gant NF, Williams Obstetrics, pp. 653-690, (1989)

[6]

Feinstein AR, Clinical Epidemiology: The architecture of clinical research, pp. 579-631, (1985)

[7]

Price RG, Dance N, Richards B, Cattell WR, The excretion of N‐acetyl‐β‐D‐glucosaminidase and β‐galactosidase following surgery to the kidney, Clin Chim Acta, 27, pp. 65-72, (1970)

← 1 →