ENZYMATIC OXIDATION OF ADENOSINE-DIPHOSPHORIBOSE

被引：3

作者：

JOHNSON, MT ^{[1
]}

GANDER, JE ^{[1
]}

机构：

[1] UNIV MINNESOTA, COLL BIOL SCI, DEPT BIOCHEM, ST PAUL, MN 55108 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1977年 / 75卷 / 03期

关键词：

D O I：

10.1016/0006-291X(77)91534-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Penicillium charlesii extracts contain UDP-galactose:NAD+ 2-hexosyl oxidoreductase. ADP-ribose serves as a substrate resulting in formation of NADH and an oxidized ADP-ribose derivative. Treatment of the oxidized product with NaBH4 followed by hydrolysis at pH 2 and 100.degree. C releases xylose as well as ribose. Apparently, ADP-D-glycero-D-glycero-3-pentosulose (ADP-3-ketoribose) is the product derived from ADP-ribose.

引用

页码：739 / 745

页数：7

共 16 条

[1]

ADAIR WL, 1973, J BIOL CHEM, V248, P4640

[2] NICOTINAMIDE MONONUCLEOTIDE ACTIVATION OF A NEW DNA-DEPENDENT POLYADENYLIC ACID SYNTHESIZING NUCLEAR ENZYME [J].

CHAMBON, P ;

MANDEL, P ;

WEILL, JD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1963, 11 (01) :39-&

[3]

DALZIEL K, 1966, BIOCHEM PREP, V11, P84

[4] PYRIDINE NUCLEOSIDASES FROM BACILLUS-SUBTILIS AND NEUROSPORA-CRASSA - ISOLATION AND STRUCTURAL-PROPERTIES [J].

EVERSE, J ;

EVERSE, KE ;

KAPLAN, NO .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1975, 169 (02) :702-713

[5] EVIDENCE FOR URIDINE 5'-(ALPHA-D-GALACTOPYRANOSYL PYROPHOSPHATE)-NAD 2-HEXOSYL OXIDOREDUCTASE IN PENICILLIUM CHARLESII [J].

FOBES, WS ;

GANDER, JE .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1972, 49 (01) :76-&

[6]

GABRIEL O, 1973, CARBOHYDRATES SOLUTI, P399

[7]

JOHNSON MT, 1976, FED PROC, V35, P1430

[8] STUDIES ON BIOCHEMISTRY OF PENICILLIUM CHARLESII - INFLUENCE OF VARIOUS DICARBOXYLIC ACIDS ON GALACTOCAROLOSE SYNTHESIS [J].

JORDAN, JM ;

GANDER, JE .

BIOCHEMICAL JOURNAL, 1966, 100 (03) :694-&

[9]

KAPLAN ND, 1973, POLY ADP RIBOSE, P5

[10]

KAPLAN NO, 1951, J BIOL CHEM, V191, P473

← 1 2 →