SUCCESSFUL TREATMENT OF PAECILOMYCES-VARIOTII INFECTION IN A PATIENT WITH CHRONIC GRANULOMATOUS-DISEASE AND A REVIEW OF PAECILOMYCES SPECIES INFECTIONS

被引：69

作者：

WILLIAMSON, PR

KWONCHUNG, KJ

GALLIN, JI

机构：

[1] NIAID, CLIN INVEST LAB, BLDG 10, ROOM 11N104, BETHESDA, MD 20892 USA

[2] NIAID, HOST DEF LAB, BETHESDA, MD 20892 USA

来源：

CLINICAL INFECTIOUS DISEASES | 1992年 / 14卷 / 05期

关键词：

D O I：

10.1093/clinids/14.5.1023

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An 8-year-old boy who had chronic granulomatous disease developed a soft tissue infection of the right heel after riding on a motor scooter. Infection was insidious, and minor heel pain and fevers occurred only on the day interferon-gamma was injected. Soft tissue biopsy showed hyphal elements, and Paecilomyces variotii grew in culture. The infection was treated with amphotericin B for 7 weeks (total dose, 40 mg/kg) followed by 1 year of therapy with itraconazole (100 mg twice daily). Complete cure was achieved during the follow-up period of 10 months.

引用

页码：1023 / 1026

页数：4

共 39 条

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