NEW INHIBITORS OF AROMATASE - SYNTHESES AND BIOLOGICAL-ACTIVITY OF PYRIDYL-SUBSTITUTED PHENANTHRENONE DERIVATIVES

被引：7

作者：

BAYER, H

HARTMANN, RW

机构：

来源：

ARCHIV DER PHARMAZIE | 1991年 / 324卷 / 11期

关键词：

D O I：

10.1002/ardp.2503241102

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The phenanthrenone derivatives 3-6 were synthesized and tested for their aromatase and desmolase inhibitory potency. Compounds 5 and 6 show a stronger inhibition of aromatase than aminoglutethimide not exceeding, however, the activity of the parent compounds 1 and 2. Compounds 4 and 5 do not inhibit desmolase.

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页码：833 / 836

页数：4

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