A CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME - THE IMPORTANCE OF HIGH-LEVELS OF WARFARIN ANTICOAGULATION

被引：22

作者：

RUFFATTI, A

DESILVESTRO, G

GHIRARDELLO, A

CALLIGARO, A

DELROSS, T

THIENE, G

TODESCO, S

机构：

[1] UNIV PADUA,IST MED INTERNA,DIV REUMATOL,PADUA,ITALY

[2] UNIV PADUA,DEPT PATHOL,I-35100 PADUA,ITALY

[3] HOSP PADOVA,BLOOD TRANSFUS SERV,PADUA,ITALY

来源：

JOURNAL OF INTERNAL MEDICINE | 1994年 / 235卷 / 01期

关键词：

ANTICOAGULANTS; ANTIPHOSPHOLIPID ANTIBODIES; ANTIPHOSPHOLIPID SYNDROME;

D O I：

10.1111/j.1365-2796.1994.tb01036.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the clinical observation of a 23-year-old woman affected by the so-called 'catastrophic antiphospholipid syndrome'. Within a 3-month period she suffered a number of thrombotic events and haemolytic anaemia with thrombocytopenia and had high levels of immunoglobulins G and M and anticardiolipin antibodies associated with lupus anticoagulant activity. The severity of the clinical and laboratory changes is described and diagnostic and therapeutic difficulties are discussed. The apparent control of thrombotic events only with high levels of warfarin anticoagulation is stressed.

引用

页码：81 / 83

页数：3

共 11 条

[1] SKIN-LESIONS ASSOCIATED WITH CIRCULATING LUPUS ANTICOAGULANT [J].