HAMACANTHIN-A AND HAMACANTHIN-B, NEW ANTIFUNGAL BIS INDOLE ALKALOIDS FROM THE DEEP-WATER MARINE SPONGE, HAMACANTHA SP

被引：110

作者：

GUNASEKERA, SP

MCCARTHY, PJ

KELLYBORGES, M

机构：

[1] Harbor Branch Oceanographic Institution, Inc., Florida 34946, 5600 U.S. I, North, Fort Pierce

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 10期

关键词：

D O I：

10.1021/np50112a014

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Hamacanthin A [1] and hamacanthin B [2] are two bioactive dihydropyrazinonediylbis(indole) alkaloids isolated from a new species of deep-water marine sponge, Hamarantha sp. The hamacanthins are growth inhibitors of Candida albicans and Cryptococncs neoformans. Isolation and structure elucidation of 1 and 2 by nmr spectroscopy are described.

引用

页码：1437 / 1441

页数：5

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