VINBLASTINE IN TREATMENT OF HODGKINS DISEASE

The author reports 126 patients with Stage III or IV Hodgkin’s disease treated with Vinblastine sulphate for at least 4 weeks. Remission of 8 weeks or longer occurred in 93 patients (74 %). Of these 32 were maintained for 6 months and 17 for 1 year. The longest remission to date is 69 months. Complications were unusual. Serious bone marrow depression occurred only in the presence of widespread disease and after previous treatment. Thrombocytopenia was not seen in association with the more temporary fluctuations in thewhite count. © 1969, The British Empire Cancer Campaign for Research. All rights reserved.