RECURRENCE OF SPINAL EPENDYMOMA - RISK-FACTORS AND LONG-TERM SURVIVAL

被引:19
作者
CERVONI, L
CELLI, P
FORTUNA, A
CANTORE, G
机构
[1] Department of Neurological Sciences and Neurosurgery, La Sapienza University of Rome, Rome
关键词
EPENDYMOMA; RECURRENCE; SPINE TUMOR;
D O I
10.1097/00007632-199412150-00019
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Design. A study was conducted on 78 patients with spinal ependymoma. The authors divided the patients in two groups. Objectives. The aim was to elicit the risk factors for recurrence and the fate of patients who underwent second operations. Summary of Background Data. Group A is made up of 59 patients with no signs of recurrence at follow-up (median 14 years), and group B is made up of 19 patients who had undergone second operations because of relapses (follow-up median 12 years). Methods. The clinical and therapeutic characteristics and survival of the two groups were compared statistically. Result. Analysis of the series shows that the most important points in predicting recurrence are length of clinical history (P < 0.05), gross appearance of the tumor at first operation (P < 0.05), and type of excision (P < 0.001). Conclusion. These factors proved to be closely interrelated. In the event of recurrence, spinal ependymoma has an adverse prognosis.
引用
收藏
页码:2838 / 2841
页数:4
相关论文
共 26 条
[1]  
Barone B.M., Elvidge A.R., Ependymomas: A clinical survey, J Neurosurg, 33, pp. 428-438, (1970)
[2]  
Cooper P.R., Outcome after operative treatment of in- tramedullary spinal cord tumors in adults: Intermediate and long-term results in 51 patients, Neurosurgery, 25, pp. 855-859, (1989)
[3]  
Van Duinen M.T.A., Van. Het ependymoom van de cauda equina, Ned Tijdschr Geneesk, 116, pp. 1649-1652, (1972)
[4]  
Garcia D.M., Primary spinal cord tumors treated with surgery and postoperative irradiation, Int J Radiat Oncol Biol Phys, 11, pp. 1933-1939, (1985)
[5]  
Guidetti B., Mercuri S., Vagnozzi R., Long-term results of the surgical treatment of 129 intramedullary spinal gliomas, J Neurosurg, 54, pp. 323-330, (1981)
[6]  
Ferrante L., Mastronardi L., Celli P., Lunardi P., Acqui M., Fortuna A., Intramedullary spinal cord ependymomas: A study of 45 cases with long-term follow-up, Acta Neurochir, 112, pp. 72-74, (1992)
[7]  
Fischer G., Tommasi M., Spinal ependymomas, Handbook of Clinical Neurology, 20, pp. 353-387, (1976)
[8]  
Fischer G., Les ependymomes intrarachidiens, Neurochir-Urgie, 23, pp. 149-236, (1977)
[9]  
Fischer G., Mansuy L., Total removal of intramedullary ependymomas: Follow-up study of 16 cases, Surg Neurol, 14, pp. 243-249, (1980)
[10]  
Ilgren E.B., Stiller C.A., Hughes J.T., Silberman D., Steckel N., Kaye A., Ependymomas: A clinical and pathologic study. Part II-Survival features, Clin Neuropathol, 3, pp. 122-127, (1984)