HETEROCYCLIC STUDIES .6. SOME 2-SUBSTITUTED DERIVATIVES ETHYL PTERIDINE-4-CARBOXYLATE

被引：9

作者：

CLARK, J

PENDERGA.W

机构：

[1] Department of Chemistry and Applied Chemistry, University of Salford

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1968年 / 09期

关键词：

D O I：

10.1039/j39680001124

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Syntheses of seven 2-substituted derivatives of ethyl pteridine-4- carboxylate (III; X = Cl, OH, OEt, NH2, NMe2, SH, or SMe) are described. The 2-hydroxy- and 2-mercapto-derivatives were obtained as 3,4-covalently hydrated species and the latter could not be dehydrated. The other compounds were prepared both as anhydrous and 5,6:7,8-dihydrated species, which were interconvertible. The influence of the 2-substituent on the position and extent of hydration is discussed. 1H N.m.r. spectra are recorded.

引用

页码：1124 / &

共 17 条

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