HORMONAL STUDY IN PATIENTS DEVELOPING AMENORRHEA DURING ADJUVANT CHEMOTHERAPY FOR BREAST-CANCER

被引：5

作者：

RECCHIONE, C ^{[1
]}

ROSSI, A ^{[1
]}

机构：

[1] IST NAZL TUMORI,DIV CLIN ONCOL F,I-20133 MILAN,ITALY

来源：

TUMORI | 1979年 / 65卷 / 01期

关键词：

D O I：

10.1177/030089167906500110

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The sera of 15 premenopausal women with operable breast cancer and who had developed amenorrhea during adjuvant chemotherapy with cyclophosphamide + methotrexate + fluorouracil were analyzed for the following hormones: 17-beta-estradiol, luteinizing hormone, thyroid stimulating hormone and prolactin. The blood levels did not differ significantly from those found in patients operated on for breast cancer and in spontaneous menopause (controls). These results suggest that the amenorrhea induced by CMF chemotherapy is of ovarian origin.

引用

页码：93 / 97

页数：5

共 15 条

[1] COMBINATION CHEMOTHERAPY AS AN ADJUVANT TREATMENT IN OPERABLE BREAST-CANCER
BONADONNA, G
BRUSAMOLINO, E
VALAGUSSA, P
ROSSI, A
BRUGNATELLI, L
BRAMBILLA, C
DELENA, M
TANCINI, G
BAJETTA, E
MUSUMECI, R
VERONESI, U
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1976, 294 (08) : 405 - 410
[2] BONADONNA G, SEMIN ONCOL
[3] USE OF POLYETHYLENE GLYCOL TO SEPARATE FREE AND ANTIBODY-BOUND PEPTIDE HORMONES IN RADIOIMMUNOASSAYS
DESBUQUOIS, B
AURBACH, GD
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1971, 33 (05) : 732 - +
[4] SURGICAL ADJUVANT CHEMOTHERAPY IN CANCER OF BREAST - RESULTS OF A DECADE OF COOPERATIVE INVESTIGATION
FISHER, B
RAVDIN, RG
AUSMAN, RK
SLACK, NH
MOORE, GE
NOER, RJ
[J]. ANNALS OF SURGERY, 1968, 168 (03) : 337 - +
[5] 1-PHENYLALANINE MUSTARD (L-PAM) IN MANAGEMENT OF PRIMARY BREAST-CANCER - REPORT OF EARLY FINDINGS
FISHER, B
CARBONE, P
ECONOMOU, SG
FRELICK, R
GLASS, A
LERNER, H
REDMOND, C
ZELEN, M
BAND, P
KATRYCH, DL
WOLMARK, N
FISHER, ER
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1975, 292 (03) : 117 - 122
[6] KOYAMA H, 1977, CANCER, V39, P1403, DOI 10.1002/1097-0142(197704)39:4<1403::AID-CNCR2820390408>3.0.CO
[7] 2-8
[8] RADIOIMMUNOASSAY - A METHOD FOR HUMAN CHORIONIC GONADOTROPIN AND HUMAN LUTEINIZING HORMONE
MIDGLEY, AR
[J]. ENDOCRINOLOGY, 1966, 79 (01) : 10 - &
[9] ODELL WD, 1967, J LAB CLIN MED, V70, P973
[10] RICCI G, 1976, BIODATA B, V1, P9

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