AMINO-ACID-SEQUENCE ELUCIDATION OF HUMAN ACROSIN-TRYPSIN INHIBITOR (HUSI-II) REVEALS THAT KAZAL-TYPE PROTEINASE-INHIBITORS ARE STRUCTURALLY RELATED TO BETA-SUBUNITS OF GLYCOPROTEIN HORMONES

被引：30

作者：

FINK, E ^{[1
]}

HEHLEINFINK, C ^{[1
]}

EULITZ, M ^{[1
]}

机构：

[1] GESELL STRAHLEN & UMWELTFORSCH MBH,INST CLIN MOLEC BIOL,W-8000 MUNICH 70,GERMANY

来源：

FEBS LETTERS | 1990年 / 270卷 / 1-2期

关键词：

Acrosin-trypsin inhibitor (human seminal plasma); Chorionic gonadotropin; Glycoprotein hormone β-subunit; Kazal-type inhibitor; Luteinizing hormone;

D O I：

10.1016/0014-5793(90)81273-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The amino acid sequence of the acrosin-trypsin inhibitor HUSI-II from human seminal plasma is presented which unequivocally identifies HUSI-II as being of Kazal-type. In addition, the HUSI-II sequence shows a striking similarity to the middle part of glycoprotein hormone β-subunits thus revealing a hitherto unknown structural and evolutionary relationship between Kazal-type inhibitors and glycoprotein hormones. © 1990.

引用

页码：222 / 224

页数：3

共 24 条

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