NEURONAL CHEMOTAXIS - CHICK DORSAL-ROOT AXONS TURN TOWARD HIGH-CONCENTRATIONS OF NERVE GROWTH-FACTOR

被引：425

作者：

GUNDERSEN, RW

BARRETT, JN

机构：

[1] Department of Physiology and Biophysics, University of Miami, School of Medicine, Miami

来源：

SCIENCE | 1979年 / 206卷 / 4422期

关键词：

D O I：

10.1126/science.493992

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Micropipettes containing 2 to 50 biological units of βnerve growth factor (NGF) were placed near growing axons of chick dorsal-root ganglion neurons in tissue culture. The axons turned and grew toward the NGF source within 21 minutes. This turning response to elevated concentrations of NGF appears to represent chemotactic guidance rather than a general enhancement of growth rate. Copyright © 1979 AAAS.

引用

页码：1079 / 1080

页数：2

共 9 条

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