MEDIUM OPTIMIZATION BY AN ORTHOGONAL ARRAY DESIGN FOR THE GROWTH OF METHANOSARCINA-BARKERI

被引：30

作者：

SILVEIRA, RG ^{[1
]}

KAKIZONO, T ^{[1
]}

TAKEMOTO, S ^{[1
]}

NISHIO, N ^{[1
]}

NAGAI, S ^{[1
]}

机构：

[1] HIROSHIMA UNIV,FAC ENGN,DEPT FERMENTAT TECHNOL,1-4-1 KAGAMIYAMA,HIROSHIMA 724,JAPAN

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1991年 / 72卷 / 01期

关键词：

D O I：

10.1016/0922-338X(91)90140-C

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Optimization of the medium composition for Methanosarcina barkeri growing on methanol (8 g/l) was carried out by two different methods, (i) "one-at-a-time" and (ii) analysis of marginal means (ANOMM) in an orthogonal array experimental design. The second method showed to be very effective in the improvement of the medium composition capable of increasing the gas production rate (CH4 + CO2) Over 1.3 and 2.0 times when compared with the "one-at-a-time" optimized medium and the basal medium, respectively.

引用

页码：20 / 25

页数：6

共 26 条

[1]

ASAO M, 1973, JIKKEN KEIKAKUHO, P105

[2] SOME STATISTICAL METHODS IN NUTRIENT MEDIUM OPTIMALISATION [J].

AUDEN, J ;

GRUNER, J ;

NUESCH, J ;

KNUSEL, F .

PATHOLOGIA ET MICROBIOLOGIA, 1967, 30 (06) :858-&

[3] EFFECTS OF CALCIUM, MAGNESIUM, PH, AND EXTENT OF GROWTH ON THE MORPHOLOGY OF METHANOSARCINA-MAZEI S-6 [J].

BOONE, DR ;

MAH, RA .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1987, 53 (07) :1699-1700

[4]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[5]

Dey A., 1985, ORTHOGONAL FRACTIONA, P1

[6] DELTA-AMINOLEVULINIC-ACID FORMATION IN THE ARCHAEBACTERIUM METHANOBACTERIUM THERMOAUTOTROPHICUM REQUIRES TRANSFER RNAGLU [J].

FRIEDMANN, HC ;

THAUER, RK ;

GOUGH, SP ;

KANNANGARA, CG .

CARLSBERG RESEARCH COMMUNICATIONS, 1987, 52 (05) :363-371

[7] KINETICS OF THE METHANOGENIC FERMENTATION OF ACETATE [J].

FUKUZAKI, S ;

NISHIO, N ;

NAGAI, S .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1990, 56 (10) :3158-3163

[8] PRODUCTION OF CELLULASES BY A WILD STRAIN OF GLIOCLADIUM-VIRENS - OPTIMIZATION OF THE FERMENTATION MEDIUM AND PARTIAL CHARACTERIZATION OF THE ENZYMES [J].

GOMES, J ;

GOMES, I ;

ESTERBAUER, H ;

KREINER, W ;

STEINER, W .

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1989, 31 (5-6) :601-608

[9]

HAALAND PD, 1990, STATISTICS TXB MONOG, V105

[10]

JEFFWU CF, 1990, STATISTICS TXB MONOG, V109, P279

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