THERAPEUTIC POTENTIAL OF CAPSAICIN-LIKE MOLECULES - STUDIES IN ANIMALS AND HUMANS

被引：50

作者：

MAGGI, CA

机构：

[1] Pharmacology Department A. Menarini Pharmaceuticals, 50131 Florence

来源：

LIFE SCIENCES | 1992年 / 51卷 / 23期

关键词：

D O I：

10.1016/0024-3205(92)90047-S

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Capsaicin-sensitive primary afferent neurons in the peripheral nervous system are widely distributed to both the somatic and visceral territories: their inactivation following capsaicin "desensitization" is expected to produce analgesia and to be useful for a number of human diseases such as asthma, urinary incontinence, inflammatory diseases of the gut, arthritis and psoriasis. The present communication reviews the therapeutic potential of capsaicin-like drugs in the pathophysiology of the mammalian urinary bladder.

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页码：1777 / 1781

页数：5

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