SIMULTANEOUS OCCURRENCE OF 5Q-IN AND 21Q-IN REFRACTORY-ANEMIA WITH THROMBOCYTOSIS

被引：27

作者：

VANDENBERGHE, H

PETIT, P

BROECKAERTVANORSHOVEN, A

LOUWAGIE, A

DEBAERE, H

VERWILGHEN, R

机构：

[1] CATHOLIC UNIV LEUVEN,DEPT HUMAN BIOL,DIV HUMAN GENET,B-3000 LOUVAIN,BELGIUM

[2] CATHOLIC UNIV LEUVEN,DEPT MED RES,DIV HEMATOL,B-3000 LOUVAIN,BELGIUM

[3] CTR DIAGNOS HORMONAL,BRUSSELS,BELGIUM

来源：

CANCER GENETICS AND CYTOGENETICS | 1979年 / 1卷 / 01期

关键词：

D O I：

10.1016/0165-4608(79)90011-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 40-yr-old female with refractory anemia and thrombocytosis was shown to possess 5q- and 21q- chromosomal anomalies in the hematopoietic cells. The former anomaly was demonstrated to be a del(5)(q14q32) and the latter to be due to a t(11;21)(q25;q21). A similar translocation was shown to exist in the cells of another patient with essential thrombocytosis. Thus, we tentatively identify the 21q- as being due to a t(11;21). © 1979.

引用

页码：63 / 68

页数：6

共 7 条

[1] CABROL C, 1978, J GENET HUM, V26, P195
[2] ASSOCIATION OF 5Q-ANEMIA AND REFRACTORY-ANEMIA
KAFFE, S
HSU, LYF
HOFFMAN, R
HIRSCHHORN, K
[J]. AMERICAN JOURNAL OF HEMATOLOGY, 1978, 4 (03) : 269 - 272
[3] PETIT P, HUM GENET
[4] SOKAL G, 1975, BLOOD, V46, P519
[5] DISTINCT HEMATOLOGICAL DISORDER WITH DELETION OF LONG ARM OF NO 5 CHROMOSOME
VANDENBERGHE, H
CASSIMAN, JJ
DAVID, G
FRYNS, JP
MICHAUX, JL
SOKAL, G
[J]. NATURE, 1974, 251 (5474) : 437 - 438
[6] SPECIFICITY OF 5Q- CHROMOSOME IN A DISTINCT TYPE OF REFRACTORY ANEMIA
VERHEST, A
VANSCHOUBROECK, F
WITTEK, M
NAETS, JP
DENOLINREUBENS, R
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1976, 56 (05) : 1053 - 1054
[7] ZACCARIA A, 1978, NEW ENGL J MED, V298, P1422

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