RATE OF URINARY UREA OUTPUT CORRELATES TO DEGREE OF MUSCULAR-ATROPHY INDUCED BY TRIAMCINOLONE ACETONIDE

被引：3

作者：

SHOJI, S

机构：

[1] Department of Medicine, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390, Japan

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1991年 / 100卷 / 03期

关键词：

D O I：

10.1016/0305-0491(91)90222-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The effect of administering triamcinolone acetonide (10 mg kg-1 day-1) as seven consecutive single daily subcutaneous injections on urinary urea output and muscular atrophy was studied in rabbits. 2. The ratio of the wet weight of the lateral vastus of the quadriceps muscle to body weight (MI) varied greatly among the rabbits. 3. The ratio of urinary urea output after to before triamcinolone injection correlated significantly to MI. 4. These findings suggest that the ratio of urinary urea output can be used as a predictive index for steroid myopathy.

引用

页码：571 / 573

页数：3

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