ALCOHOL-CONSUMPTION AS A MODIFIER OF THE RELATION BETWEEN BLOOD LEAD AND BLOOD-PRESSURE

被引：8

作者：

HENSE, HW

FILIPIAK, B

KEIL, U

机构：

[1] GSF-Forschungszentrum für Umwelt und Gesundheit, Institut für Epidemiologie, Munich-Neuherberg

[2] Ruhr-Universität Bochum, Abteilung für Sozialmedizin und Epidemiologie, Bochum

[3] Westfälische Wilhelms-Universität Münster, Institut für Epidemiologie und Sozialmedizin, Münster

来源：

EPIDEMIOLOGY | 1994年 / 5卷 / 01期

关键词：

LEAD; BLOOD PRESSURE; ALCOHOL; EFFECT MODIFICATION; POPULATION SURVEY; URBANIZATION; GENDER;

D O I：

10.1097/00001648-199401000-00018

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Hypothetically, blood lead may be involved in blood pressure elevations owing to a facilitation of vascular adrenergic stimulation by extrinsic factors like alcohol. We therefore investigated whether self-reported alcohol consumption was a modifier of the blood lead-blood pressure relation in 3,664 men and women, age 28-67 years, from the MONICA Augsburg study in Germany. In women, only heavy drinkers (40 gm alcohol per day or more) showed a strong relation of blood lead with systolic and diastolic blood pressure, whereas little association was observed for abstaining and for moderately drinking women. In men, we found similar alcohol modifications of the lead-pressure relation only for those with rural, rather than urban, places of residence. We have no explanation for this subgroup divergence. Our results may be taken to indicate a possible role of alcohol consumption in modifying the action of lead on blood pressure.

引用

页码：120 / 123

页数：4

共 19 条

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