6-HALOPURINES IN PALLADIUM-CATALYZED COUPLING WITH ORGANOTIN AND ORGANOZINC REAGENTS

被引：97

作者：

GUNDERSEN, LL

BAKKESTUEN, AK

AASEN, AJ

OVERAS, H

RISE, F

机构：

[1] UNIV OSLO,DEPT PHARM,N-0316 OSLO,NORWAY

[2] UNIV OSLO,DEPT CHEM,N-0315 OSLO,NORWAY

来源：

TETRAHEDRON | 1994年 / 50卷 / 32期

关键词：

D O I：

10.1016/S0040-4020(01)85540-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-9 and N-7 benzylated 6-halopurines readily participate in palladium catalyzed cross coupling reactions with organotin and organozinc derivatives. In most instances the 6-chloropurines can be used. Organostannanes are excellent reagents for the introduction of alkenyl and aryl substituents, but organozinc compounds are the reagents of choice for the introduction of alkyl groups.

引用

页码：9743 / 9756

页数：14

共 36 条

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