SHORT ECHO TIME PROTON SPECTROSCOPY OF THE BRAIN IN HEALTHY-VOLUNTEERS USING AN INSERT GRADIENT HEAD COIL

被引:6
作者
GIDEON, P
DANIELSEN, ER
SCHNEIDER, M
HENRIKSEN, O
机构
[1] Danish Research Center of Magnetic Resonance, Hvidovre University Hospital, Copenhagen
[2] Siemens AG, Medical Engineering Group, Erlangen
关键词
PROTON SPECTROSCOPY; STIMULATED ECHO ACQUISITION MODE (STEAM); SHORT ECHO TIME; BRAIN; GRADIENT HEAD COIL;
D O I
10.1016/0730-725X(94)00073-C
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
An insert gradient head coil with built-in X, Y, and Z gradients was used for localized proton spectroscopy in the brain of healthy volunteers, using short echo time stimulated echo acquisition mode (STEAM) sequences. Volume of interest size was 3.4 ml, repetition time was 6.0 s, and echo times were 10 and 20 ms, respectively. Good quality proton spectra with practically no eddy current artefacts were acquired allowing observation of strongly coupled compounds, and compounds with short T-2 relaxation times. The gradient head coil thus permits further studies of compounds such as glutamine/glutamate and myo-inositols. These compounds were more prominent within grey matter than within white matter. Rough estimations of metabolite concentrations using water as an internal standard were in good agreement with previous reports.
引用
收藏
页码:105 / 109
页数:5
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