(E)-4-(ALPHA-HALO-PARA-TOLYL)-2-OXO-3-BUTENOIC ACIDS INHIBIT YEAST PYRUVATE DECARBOXYLASE BY A DIVERSITY OF MECHANISMS - MULTIPLE FATE FOR THE THIAMINE-BOUND ENAMINE INTERMEDIATE

被引：39

作者：

ANNAN, N ^{[1
]}

PARIS, R ^{[1
]}

JORDAN, F ^{[1
]}

机构：

[1] RUTGERS STATE UNIV,DEPT CHEM,NEWARK,NJ 07102

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1989年 / 111卷 / 24期

关键词：

D O I：

10.1021/ja00206a019

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：8895 / 8901

页数：7

共 18 条

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[3] INHIBITION OF BENZOYLFORMATE DECARBOXYLASE BY [PARA-(BROMOMETHYL)BENZOYL]FORMATE - ENZYME-CATALYZED MODIFICATION OF THIAMINE PYROPHOSPHATE BY HALIDE ELIMINATION AND TAUTOMERIZATION
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[4] THIAMIN DIPHOSPHATE CATALYSIS - MECHANISTIC DIVERGENCE AS A PROBE OF SUBSTRATE ACTIVATION OF PYRUVATE DECARBOXYLASE
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[5] HUBNER G, 1988, THIAMINE PYROPHOSPHA, V1, P93
[6] ENZYME-GENERATED MODEL FOR THE REDUCTIVE ACETYLATION OF LIPOYL-E2 BY E1 IN THE PYRUVATE-DEHYDROGENASE MULTIENZYME COMPLEX
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[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1986, 471 : 308 - 309
[7] NUCLEAR-MAGNETIC-RESONANCE DETERMINATION OF THE SITE OF ACYLATION OF THE TAUTOMERIC NUCLEOPHILE 4-THIOXOPYRIDINE
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[8] Jordan F, 1986, J Enzyme Inhib, V1, P139, DOI 10.3109/14756368609020112
[9] JORDAN F, 1988, THIAMINE PYROPHOSPHA, V1, P79
[10] KUO DJ, 1986, J BIOL CHEM, V261, P3316

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