DEAFFERENTATION IN THE RAT INCREASES MECHANICAL NOCICEPTIVE THRESHOLD IN THE INNERVATED LIMBS

被引：25

作者：

KAYSER, V

BASBAUM, AI

GUILBAUD, G

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHYSIOL,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT ANAT,SAN FRANCISCO,CA 94143

来源：

BRAIN RESEARCH | 1990年 / 508卷 / 02期

关键词：

Cervical dorsal rhizotomy; Deafferentation; Nociceptive threshold;

D O I：

10.1016/0006-8993(90)90418-B

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this study in the rat, we evaluated the effect of unilateral, multiple cervical dorsal rhizotomy (C5-T1) on nociceptive thresholds in the unoperated limbs. This was tested by measuring the vocalization threshold to paw pressure. We report that deafferentation by dorsal rhizotomy results in a delayed, but transient increase in mechanical nociceptive thresholds in the 3 innervated limbs. © 1990.

引用

页码：329 / 332

页数：4

共 21 条

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