STRUCTURE OF ALPHA-ALPHA-HAIRPINS WITH SHORT CONNECTIONS

被引：75

作者：

EFIMOV, AV

机构：

[1] Institute of Protein Research, Academy of Sciences of the USSR, 142292 Pushchino, Moscow Region

来源：

PROTEIN ENGINEERING | 1991年 / 4卷 / 03期

关键词：

AMINO ACID SEQUENCE; CONFORMATION; ALPHA-ALPHA-HAIRPIN; ALPHA-HELIX; STEREOCHEMICAL ANALYSIS;

D O I：

10.1093/protein/4.3.245

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper presents the results of detailed stereochemical analysis of structures and sequences of alpha-alpha-hairpins with short connections. It is shown that alpha-alpha-hairpins of each given type have very similar patterns of hydrophobic, hydrophilic and glycine residues in their amino acid sequences. These results can be used in the prediction of alpha-alpha-hairpin conformation as well as in protein design and engineering.

引用

页码：245 / 250

页数：6

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