SYNTHESIS OF 2,5-DIDEOXY-4,6-DI-O-(2,3-DIDEOXY-ALPHA-D-ERYTHRO-HEXOPYRANOSYL)STREPTAMINE AND 4,6-DI-O-(6-AMINO-2,3,6-TRI-DEOXY-ALPHA-D-ERYTHRO-HEXOPYRANOSYL)-2,5-DIDEOXYSTREPTAMINE

被引:11
作者
CANASRODRIGUEZ, A
MARTINEZTOBED, A
机构
[1] Pharmacy Department, Chelsea College (University of London), London
关键词
D O I
10.1016/S0008-6215(00)84053-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The title pseudotrisaccharides, derived from 2,5-dideoxystreptamine, have been synthesized, in order to ascertain structure-activity relationships in aminoglycoside antibiotics. High yields of α-D-glycosides, virtually free of β anomers, were achieved by the BF3-catalyzed addition of alcohols to glycals. © 1979.
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页码:43 / 53
页数:11
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