INTERACTION BETWEEN BETA-1 AND BETA-2 ADRENOCEPTORS IN THE ISOLATED GUINEA-PIG TRACHEA

被引：12

作者：

OMINI, C

SOMERVILLE, AR

FOLCO, GC

ROSSONI, G

PUGLISI, L

机构：

[1] Institute of Pharmacology, Pharmacognosv University, Milan School of Pharmacy

来源：

PHARMACOLOGICAL RESEARCH COMMUNICATIONS | 1979年 / 11卷 / 06期

关键词：

D O I：

10.1016/S0031-6989(79)80025-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The presence of .beta.1 and .beta.2 adrenoceptors was demonstrated in guinea-pig tracheal smooth muscle and both receptors subserve the same function. The functional relationship between the two .beta.-receptors in the guinea-pig trachea, which is difficult to explain, is discussed in relation to the capacity of .beta.1 receptors to take over their function, if the .beta.2 receptors are completely blocked. Atenolol, practolol, salbutamol, clenbuterol, pilocarpine, L-isoproterenol and ICI 118,551 were used.

引用

页码：529 / 535

页数：7

共 8 条

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