ENANTIOMER RESOLUTION BY USING CAPILLARY ZONE ELECTROPHORESIS - RESOLUTION OF RACEMIC TRYPTOPHAN AND DETERMINATION OF THE ENANTIOMER COMPOSITION OF COMMERCIAL PHARMACEUTICAL EPINEPHRINE

The enantiomers of D‐ and L‐tryptophan were separated by capillary electrophoresis, using α‐cyclodextrin as a chiral active component in the background electrolyte. The separation of (‐) and (+) epinephrine was achieved by supplementing the background electrolyte with Heptakis (2,6‐di‐O‐methyl‐β‐cyclodextrin). As a practical application of the method, the quantitative analysis of (‐)and(+)enantiomers in commercial pharmaceutical solutions of adrenaline is shown. Copyright © 1990 VCH Verlagsgesellschaft mbH