THE ASSOCIATION BETWEEN ALCOHOL, HEPATIC PATHOLOGY AND DUPUYTRENS DISEASE

被引：49

作者：

NOBLE, J ^{[1
]}

ARAFA, M ^{[1
]}

ROYLE, SG ^{[1
]}

MCGEORGE, G ^{[1
]}

CRANK, S ^{[1
]}

机构：

[1] UNIV MANCHESTER,DEPT ORTHOPAED SURG,MANCHESTER M13 9PL,LANCS,ENGLAND

来源：

JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME | 1992年 / 17B卷 / 01期

关键词：

D O I：

10.1016/0266-7681(92)90015-T

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We have looked at the incidence of Dupuytren's disease in alcoholics, those with non-alcoholic liver disease and a control population. Both alcoholic patients and those with non-alcohol related liver disease had a higher rate (28% and 22% respectively) than the controls (8%), but this did not quite reach statistical significance (p > 0.05). In addition we found no Dupuytren's disease in 50 Egyptian patients with bilharzia and no consistent biochemical abnormalities in 134 patients with significant Dupuytren's disease. We conclude that alcoholics probably do have a higher rate of Dupuytren's disease and that this effect is largely due to the liver disease caused by alcohol abuse, but that the genetic factors are of greater aetiological importance.

引用

页码：71 / 74

页数：4

共 11 条

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