STRUCTURE-ACTIVITY RELATIONSHIPS IN DRUG-INDUCED PANCREATIC-ISLET CELL TOXICITY

被引：16

作者：

FISCHER, LJ ^{[1
]}

WOLD, JS ^{[1
]}

RICKERT, DE ^{[1
]}

机构：

[1] UNIV IOWA,TOXICOL CTR,COLL MED,DEPT PHARMACOL,IOWA CITY,IA 52240

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1973年 / 26卷 / 02期

关键词：

D O I：

10.1016/0041-008X(73)90264-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：288 / 298

页数：11

共 8 条

[1] 7SUBCHRONIC TOXICITY OF 5-BENZYL-11-[4-(N-METHYL-PIPERIDYLENE)]-5,6-DIHYDROMORPHANTHRIDINE HYDROGEN MALEATE [J].

BELILES, RP .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1971, 18 (02) :451-&

[2]

DUBOWSKI KM, 1962, CLIN CHEM, V8, P215

[3] STRUCTURE-ACTIVITY RELATIONSHIPS IN CYPROHEPTADINE SERIES [J].

ENGELHARDT, EL ;

ZELL, HC ;

SAARI, WS ;

CHRISTY, ME ;

COLTON, CD .

JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (06) :829-+

[4] INVESTIGATIONS INTO METABOLIC FATE AND DISTRIBUTION OF HEPZIDINE MALEATE IN RAT AND MOUSE [J].

HESPE, W ;

PRINS, H ;

KAFOE, WF ;

NAUTA, WT .

BIOCHEMICAL PHARMACOLOGY, 1968, 17 (05) :655-&

[5]

HRUBAN A, 1972, LAB INVEST, V26, P270

[6] ULTRASTRUCTURAL STUDY OF ALTERATIONS IN BETA CELLS OF PANCREATIC-ISLETS FROM CYPROHEPTADINE-TREATED RATS [J].

LONGNECKER, DS ;

WOLD, JS ;

FISCHER, LJ .

DIABETES, 1972, 21 (02) :71-+

[7] SPECIES DEPENDENT PANCREATIC ISLET TOXICITY PRODUCED BY CYPROHEPTADINE - ALTERATIONS IN BETA CELL STRUCTURE AND FUNCTION [J].

WOLD, JS ;

LONGNECKER, DS ;

FISCHER, LJ .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1971, 19 (02) :188-+

[8]

WOLD JS, 1972, J PHARMACOL EXP THER, V183, P188

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