Scanning tunnelling microscopy imaging of the DNA base molecules on reduced SrTiO3(100) surfaces

被引:18
作者
Tanaka, H [1 ]
Kawai, T [1 ]
机构
[1] OSAKA UNIV,INST SCI & IND RES,IBARAKI,OSAKA 567,JAPAN
来源
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC MATERIALS SENSORS AND SYSTEMS | 1995年 / 3卷 / 02期
关键词
DNA base molecules; ultrahigh vacuum; lateral dimensions; scanning tunnelling microscopy;
D O I
10.1016/0928-4931(95)00119-0
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The four DNA bases, adenine, guanine, thymine and cytosine, have been deposited on a reduced SrTiO3 (100) substrate and been observed by scanning tunnelling microscopy (STM) in ultrahigh vacuum (UHV) conditions. The images indicate that the bases are deposited as individual molecules in UHV conditions, and can be individually observed by STM. The lateral dimensions of adenine and guanine are 1.5-1.0 nm and of thymine and cytosine are 1.0-0.6 nm with a sample bias voltage from -1 to -3 V. It has been revealed that a comparison of the heights and lateral dimensions of the deposited species, and also of the bias dependence of the heights, allows differentiation between the four DNA bases in real space.
引用
收藏
页码:143 / 148
页数:6
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