BIOTRANSFORMATION OF AJMALINE IN PLANT-CELL CULTURES OF RAUWOLFIA-SERPENTINA BENTH - THE NEW INDOLE ALKALOIDS RAUMACLINE AND N(B)-METHYLRAUMACLINE

被引：30

作者：

POLZ, L

STOCKIGT, J

TAKAYAMA, H

UCHIDA, N

AIMI, N

SAKAI, S

机构：

[1] UNIV MUNICH, INST PHARMACEUT BIOL, KARLSTR 29, W-8000 MUNICH 2, GERMANY

[2] CHIBA UNIV, FAC PHARMACEUT SCI, CHIBA 260, JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)97149-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two novel indole alkaloids, raumacline (2) and N(b)-methylraumacline (3), were isolated from plant cell cultures of Rauwolfia serpentina Benth. after feeding experiments with the Rauwolfia alkaloid ajmaline (1). The structures of the new alkaloids were elucidated by spectroscopic methods and chemical synthesis from ajmaline (1). © 1990.

引用

页码：6693 / 6696

页数：4

共 20 条

[1] RAUWOLFIA ALKALOIDS .48. OXIDATIVE DEMETHYLATION + REARRANGEMENT OF SOME AJMALINE DERIVATIVES [J].