BACTERICIDAL ACTIVITY OF SERA OF HEALTHY NEONATES AND OF NEWBORNS WITH HYPERBILIRUBINEMIA TO ESCHERICHIA-COLI

被引：29

作者：

MILER, I

VONDRACEK, J

HROMADKOVA, L

机构：

[1] Research Institute for the Care of Mother and Child, Prague 4

来源：

FOLIA MICROBIOLOGICA | 1979年 / 24卷 / 02期

关键词：

D O I：

10.1007/BF02927298

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Cord and newborn sera were found to possess a significantly decreased in vitro bactericidal Activity to Escherichia coli as compared to sera of adult individuals. Hyperbilirubinaemia in neonates suffering from both Rh and ABO incompatibility results in a further significant impairment of the bactericidal activity of their sera in comparison with healthy newborn infants. Exchange transfusion improved considerably the serum bactericidal activity. The possible mechanism of toxic action of unconjugated bilirubin on cells of the immune system is discussed. © 1979 Institute of Microbiology, Academy of Sciences of the Czech Republic.

引用

页码：143 / 152

页数：10

共 58 条

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