HIGH PREVALENCE OF ANTI-HEPATITIS DELTA VIRUS-ANTIBODY IN CHRONIC LIVER-DISEASE IN SOMALIA

被引：6

作者：

ACETI, A

MOHAMED, OM

PAPARO, BS

MOHAMUD, OM

QUARANTA, G

MAALIN, KA

SEBASTIANI, A

机构：

[1] UNIV ROME LA SAPIENZA,INST CLIN TROP & INFECT DIS,I-00185 ROME,ITALY

[2] SOMALI NATL UNIV,FAC MED,MUQDISHO,SOMALIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1991年 / 85卷 / 04期

关键词：

D O I：

10.1016/0035-9203(91)90249-X

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We have assessed the prevalence of hepatitis delta virus (HDV) infection in people with histologically proven chronic liver disease living in Somalia. Among 104 patients studied (14 with chronic persistent hepatitis, 74 with chronic active hepatitis, and 16 with active cirrhosis), 52 were positive for hepatitis B surface antigen; of these 26 (50%) carried anti-delta antibodies. HDV infection was detected more frequently in sera from hepatitis B e antigen (HBeAG) negative patients (60.9%) than in HBeAG positive patients (9.1%). Using the dot-blot hybridization technique, serum hepatitis B virus deoxyribonucleic acid was revealed in 73.1% of patients without HDV infection, while it was detected in only 7.7% of anti-delta positive patients. It is concluded that HDV is strongly associated with chronic liver disease in Somalia.

引用

页码：541 / 542

页数：2

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