INVITRO AND INVIVO INHIBITION OF RAT-LIVER ALDEHYDE DEHYDROGENASE BY S-METHYL N,N-DIETHYLTHIOLCARBAMATE SULFOXIDE, A NEW METABOLITE OF DISULFIRAM

被引：81

作者：

HART, BW ^{[1
]}

FAIMAN, MD ^{[1
]}

机构：

[1] UNIV KANSAS,DEPT PHARMACOL & TOXICOL,LAWRENCE,KS 66045

来源：

BIOCHEMICAL PHARMACOLOGY | 1992年 / 43卷 / 03期

关键词：

D O I：

10.1016/0006-2952(92)90555-W

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：403 / 406

页数：4

共 10 条

[1]

FAIMAN MD, 1978, RES COMMUN CHEM PATH, V21, P543

[2] DIETHYLDITHIOCARBAMIC ACID METHYL-ESTER - METABOLITE OF DISULFIRAM [J].

GESSNER, T ;

JAKUBOWSKI, M .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (02) :219-+

[3] S-METHYL-N,N-DIETHYLTHIOLCARBAMATE - A DISULFIRAM METABOLITE AND POTENT RAT-LIVER MITOCHONDRIAL LOW KM ALDEHYDE DEHYDROGENASE INHIBITOR [J].

HART, BW ;

YOURICK, JJ ;

FAIMAN, MD .

ALCOHOL, 1990, 7 (02) :165-169

[4]

HART BW, 1988, ALCOHOL CLIN EXP RES, V12, P317

[5] DIETHYLTHIOCARBAMIC ACID METHYL-ESTER - A POTENT INHIBITOR OF ALDEHYDE DEHYDROGENASE FOUND IN RATS TREATED WITH DISULFIRAM OR DIETHYLDITHIOCARBAMIC ACID METHYL-ESTER [J].

JOHANSSON, B ;

PETERSEN, EN ;

ARNOLD, E .

BIOCHEMICAL PHARMACOLOGY, 1989, 38 (07) :1053-1059

[6]

KITSON TM, 1989, HUMAN METABOLISM ALC, V2, P117

[7] SUBCELLULAR-DISTRIBUTION AND PROPERTIES OF ALDEHYDE DEHYDROGENASES IN RAT-LIVER [J].

TOTTMAR, SOC ;

PETTERSSON, H ;

KIESSLING, KH .

BIOCHEMICAL JOURNAL, 1973, 135 (04) :577-586

[8] COMPARATIVE ASPECTS OF DISULFIRAM AND ITS METABOLITES IN THE DISULFIRAM ETHANOL REACTION IN THE RAT [J].

YOURICK, JJ ;

FAIMAN, MD .

BIOCHEMICAL PHARMACOLOGY, 1989, 38 (03) :413-421

[9] DISULFIRAM METABOLISM AS A REQUIREMENT FOR THE INHIBITION OF RAT-LIVER MITOCHONDRIAL LOW KM ALDEHYDE DEHYDROGENASE [J].

YOURICK, JJ ;

FAIMAN, MD .

BIOCHEMICAL PHARMACOLOGY, 1991, 42 (07) :1361-1366

[10] DIETHYLDITHIOCARBAMIC ACID-METHYL ESTER - A METABOLITE OF DISULFIRAM AND ITS ALCOHOL SENSITIZING PROPERTIES IN THE DISULFIRAM-ETHANOL REACTION [J].

YOURICK, JJ ;

FAIMAN, MD .

ALCOHOL, 1987, 4 (06) :463-467

← 1 →