EFFICACY OF LOW-DOSES OF PRAZIQUANTEL IN TAENIASIS

被引：31

作者：

PAWLOWSKI, ZS

机构：

[1] Clinic of Parasitic and Tropical Diseases, Academy of Medicine, Poznan

来源：

ACTA TROPICA | 1990年 / 48卷 / 02期

关键词：

Low dose; Praziquantel; Taeniasis in man;

D O I：

10.1016/0001-706X(90)90046-3

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Early experimental studies suggested that doses of 1 to 5 mg of praziquantel (PZQ) per kg are effective against several intestinal cestodiases. The usually recommended single dose of PZQ in human taeniasis is 5 or 10 mg/kg. A study in T. saginata taeniasis showed a full efficacy at a dose of 2.5 mg/kg. A field study confirmed that a dose between 3.4 and 7.5 mg/kg was effective in expulsion T. solium tapeworms in man. A dose of 2.5 mg of PZQ per kg would be safer and more economical in population-oriented interventions aiming at control of T. solium taeniasis in man. © 1990.

引用

页码：83 / 88

页数：6

共 28 条

[1]

Andrews P., 1976, Veterinary Medical Review, P154

[2]

ANDREWS P, 1979, TROPENMED PARASITOL, V30, P391

[3] EFFICIENCY OF PRAZIQUANTEL, A NEW CESTICIDE, AGAINST TAENIA-HYDATIGENA IN DOG [J].

BALDOCK, FC ;

FLUCKE, WJ ;

HOPKINS, TJ .

RESEARCH IN VETERINARY SCIENCE, 1977, 23 (02) :237-238

[4]

BARANSKI M C, 1977, Boletin Chileno de Parasitologia, V32, P37

[5]

BUNNAG D, 1981, Southeast Asian Journal of Tropical Medicine and Public Health, V12, P413

[6]

COPELMAN H, 1983, FOLHA MED, V86, P87

[7]

CRUZ M, 1989, B WORLD HEALTH ORGAN, V67, P401

[8]

de Rezende G L, 1983, Bol Chil Parasitol, V38, P52

[9]

FAN P C, 1986, Southeast Asian Journal of Tropical Medicine and Public Health, V17, P82

[10]

Garbe, 1976, EUR J DRUG METAB PH, V1, P85, DOI DOI 10.1007/BF03189262

← 1 2 3 →