PSEUDOCYSTS IN CHRONIC-PANCREATITIS - A MORPHOLOGICAL ANALYSIS OF 57 RESECTION SPECIMENS AND 9 AUTOPSY PANCREASES

被引：123

作者：

KLOPPEL, G

MAILLET, B

机构：

[1] Department of Pathology, Academic Hospital, Free University of Brussels, Brussels

来源：

PANCREAS | 1991年 / 6卷 / 03期

关键词：

CHRONIC PANCREATITIS; PSEUDOCYST; STRUCTURE; INCIDENCE OF PSEUDOCYST; PATHOGENETIC SIGNIFICANCE;

D O I：

10.1097/00006676-199105000-00003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The pathology of chronic pancreatitis is reviewed in order to study the histology and incidence of pseudocysts in relation to the degree of pancreatic fibrosis and calcification. The series consisted of 57 resection specimens (49 partial pancreatectomy specimens and 8 total pancreatectomy specimens) and 9 autopsy pancreata. The histology of cystic lesions observed in the specimens was found to be identical to that of pseudocysts in acute pancreatitis. In 19 of 57, there was concomitant occurrence of focal autodigestive (fat) necrosis and pseudocysts. Pseudocysts were more common in specimens with focal fibrosis and few calcifications (13/25) than in those with diffuse advanced fibrosis and numerous calcifications (15/41). The findings indicate that sequelae of acute pancreatitis are frequently present in chronic pancreatitis, particularly in an early stage when fibrosis is still focal and calcification rare. This suggests that chronic pancreatitis may result from relapses of severe acute pancreatitis. A pathogenetic concept that relates acute pancreatitis with chronic pancreatitis is proposed.

引用

页码：266 / 274

页数：9

共 26 条

[1] Gyr K., Singer M.V., Sarles H., Pancreatitis. Concepts and classification, Proceedings of the Second International Symposium on the Classification of Pancreatitis, (1984)
[2] Ammann R.W., Muench R., Otto R., Buehler H., Freiburghaus A.U., Siegenthaler W., Evolution and regression of pancreatic calcification in chronic pancreatitis. A prospective longterm study of 107 patients, Gastroenterology, 95, pp. 1018-1028, (1988)
[3] Gilinsky N.H., Leung J., Heron C., Cotton P.B., Calcific pancreatitis: Calcification patterns and pancreatogram correlations, Clin Radiol, 35, pp. 401-404, (1984)
[4] Viswanathan M., Pancreatic diabetes in India: An overview, Secondary Diabetes: The Spectrum of The Diabetic Syndromes, pp. 105-116, (1980)
[5] Gyr K., Heitz P.U., Beglinger C., Pancreatitis, Pancreatic Pathology, pp. 44-72, (1984)
[6] Sarles H., Chronic pancreatitis: Etiology and pathophysiology, The Exocrine Pancreas. Biology, Pathobiology, and Diseases, pp. 527-575, (1986)
[7] Guy O., Robles-Diaz G., Adrich Z., Sahel J., Sarles H., Protein content of precipitates present in pancreatic juice of alcoholic subjects and patients with chronic calcifying pancreatitis, Gastroenterology, 84, pp. 102-107, (1983)
[8] Sarles H., Sarles J.C., Camatte R., Et al., Observations on 205 confirmed cases of acute pancreatitis, recurring pancreatitis and chronic pancreatitis, Gut, 6, pp. 545-559, (1965)
[9] Stolte M., Chronische Pankreatitis: Morphologie, Pank-Reatographie, Differentialdiagnose, (1984)
[10] Becker V., Chronische Pankreatitis. Klinische Morphologie, Gastroenterologie Und Stoffwechsel, 21, (1984)

← 1 2 3 →