INHIBITORS OF CALCIUM-OXALATE CRYSTALLIZATION AND UROLITHIASIS

被引：10

作者：

GRASES, F

CONTE, A

GENESTAR, C

COSTABAUZA, A

机构：

[1] Department of Chemistry, University of the Balearic Islands. and Urology Service, Hospital General ‘Virgcn de Lluch’ (Insalud), Palma de Mallorca

来源：

UROLOGIA INTERNATIONALIS | 1992年 / 48卷 / 04期

关键词：

CITRATE; MAGNESIUM; PYROPHOSPHATE; CHONDROITIN SULFATE; CALCIUM OXALATE; UROLITHIASIS;

D O I：

10.1159/000282365

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

In urolithogenic processes both, promoters and deficit of inhibitors, play an important role. The inhibitory action of added inhibitors (magnesium, citrate, pyrophosphate and chondroitin sulphate) was investigated using the urine of 72 patients with calcium urolithiasis. It was concluded that the deficit of inhibitors seems to be an important cause of stone formation in idiopathic oxalocalcic urolithiasis. Nevertheless, when that specific heterogeneous nucleation takes place it becomes an important factor and the inhibitor plays a complementary role in calcium oxalate urolithiasis.

引用

页码：409 / 414

页数：6

共 22 条

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