NOVEL METHODS FOR SYNTHESES OF SUBSTITUTED OXAZOLES BY CYCLIZATION OF VINYL BROMIDES

被引：39

作者：

DAS, J

REID, JA

KRONENTHAL, DR

SINGH, J

PANSEGRAU, PD

MUELLER, RH

机构：

[1] Bristol-Myers Squibb, Pharmaceutical Research Institute, Princeton, NJ 08543-4000

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)74756-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several methods for converting vinyl bromides and vinyl dibromides to oxazoles are described. Cyclization of vinyl bromide 6 with cesium carbonate in dioxane forms oxazole 7 while 6 is converted to the corresponding bromooxazole 12 by treatment with CuBr2/DBU.

引用

页码：7835 / 7838

页数：4

共 21 条

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