THE LEARNING-ABILITY AND MOTILITY OF SENESCENCE ACCELERATED MICE (SAM-P/1) TREATED WITH TOKI-SHAKUYAKU-SAN

被引:5
作者
KISHIKAWA, M
NISHIMURA, M
SAKAE, M
ISEKI, M
机构
[1] Department of Pathology, Scientific Data Center for the Atomic Bomb Disaster, Nagasaki University School of Medicine, Nagasaki, 852
关键词
SENESCENCE ACCELERATED MOUSE; KAMPO MEDICINE; LEARNING ABILITY; PASSIVE AVOIDANCE TASK;
D O I
10.1002/ptr.2650070719
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The effects of the Kampo medicine Toki-Shakuyaku-San on the motility and learning ability of mice were studied. An assay on mice aged 5 months after 15 weeks of administration revealed no change in spontaneous motility. However, in a study on learning ability employing passive avoidance task, the latent periods of test trial were significantly longer in the Toki-Shakuyaku-San administered group than in a control group, indicating that Toki-Shakuyaku-San may play some role in the alleviation of learning disturbances in mice.
引用
收藏
页码:S63 / S66
页数:4
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