EVALUATION OF ALTERNARIOL AND ALTERNARIOL METHYL-ETHER FOR MUTAGENIC ACTIVITY IN SALMONELLA-TYPHIMURIUM

被引：35

作者：

DAVIS, VM ^{[1
]}

STACK, ME ^{[1
]}

机构：

[1] US FDA, DIV CONTAMINANTS CHEM, WASHINGTON, DC 20204 USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 1994年 / 60卷 / 10期

关键词：

D O I：

10.1128/AEM.60.10.3901-3902.1994

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Alternariol and alternariol methyl ether were tested in the Ames Salmonella typhimurium assay, and both were shown, with and without metabolic activation, to be nonmutagenic to strains TA98 and TA100. The finding of other investigators that alternariol methyl ether is weakly mutagenic to TA98 without metabolic activation could have resulted from the presence of a small amount of one of the highly mutagenic altertoxins in the alternariol methyl ether originally tested.

引用

页码：3901 / 3902

页数：2

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