OXYTOCIN ENHANCES, AND OXYTOCIN ANTAGONISM DECREASES, SEXUAL RECEPTIVITY IN INTACT FEMALE RATS

被引：31

作者：

BENELLI, A ^{[1
]}

POGGIOLI, R ^{[1
]}

LUPPI, P ^{[1
]}

RUINI, L ^{[1
]}

BERTOLINI, A ^{[1
]}

ARLETTI, R ^{[1
]}

机构：

[1] UNIV MODENA, DEPT BIOMED SCI, PHARMACOL SECT, I-41100 MODENA, ITALY

来源：

NEUROPEPTIDES | 1994年 / 27卷 / 04期

关键词：

D O I：

10.1016/0143-4179(94)90005-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In intact, non-ovariectomized female rats in spontaneous behavioral estrus, the i.c.v. injection of oxytocin significantly increased lordosis quotient and lordosis duration, starting from a dose of 1 ng/rat. On the other hand, the oxytocin antagonist, d(CH2)(5)Tyr(Me)-[Orn](8)-vasotocin, injected at the same doses and by the same route, decreased lordosis quotient and lordosis duration, and prevented the effect of oxytocin. These data further support the notion that oxytocin plays a physiological role in female sexual receptivity.

引用

页码：245 / 250

页数：6

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