METHOTREXATE-RESISTANT CHINESE-HAMSTER OVARY CELLS HAVE AMPLIFIED A 135-KILOBASE-PAIR REGION THAT INCLUDES THE DIHYDROFOLATE-REDUCTASE GENE

被引：143

作者：

MILBRANDT, JD ^{[1
]}

HEINTZ, NH ^{[1
]}

WHITE, WC ^{[1
]}

ROTHMAN, SM ^{[1
]}

HAMLIN, JL ^{[1
]}

机构：

[1] UNIV VIRGINIA, SCH MED, DEPT BIOCHEM, CHARLOTTESVILLE, VA 22908 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1981年 / 78卷 / 10期

关键词：

D O I：

10.1073/pnas.78.10.6043

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：6043 / 6047

页数：5

共 20 条

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[6] PHENOTYPIC EXPRESSION IN ESCHERICHIA-COLI OF A DNA-SEQUENCE CODING FOR MOUSE DIHYDROFOLATE-REDUCTASE
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[7] CORRELATION OF DIHYDROFOLATE-REDUCTASE ELEVATION WITH GENE AMPLIFICATION IN A HOMOGENEOUSLY STAINING CHROMOSOMAL REGION IN L5178Y CELLS
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[J]. JOURNAL OF CELL BIOLOGY, 1979, 83 (02) : 394 - 402
[8] REPLICATION PATTERN OF A LARGE HOMOGENOUSLY STAINING CHROMOSOME REGION IN ANTIFOLATE-RESISTANT CHINESE-HAMSTER CELL-LINES
HAMLIN, JL
BIEDLER, JL
[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 1981, 107 (01) : 101 - 114
[9] Kates J, 1973, Methods Cell Biol, V7, P53
[10] CLEAVAGE OF STRUCTURAL PROTEINS DURING ASSEMBLY OF HEAD OF BACTERIOPHAGE-T4
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[J]. NATURE, 1970, 227 (5259) : 680 - +

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