EFFECT OF VARYING AMOUNTS OF ETHINYL ESTRADIOL IN THE COMBINED ORAL-CONTRACEPTIVE ON PLASMA SEX-HORMONE BINDING GLOBULIN CAPACITY IN NORMAL WOMEN

被引：11

作者：

POGMORE, JR

JEQUIER, AM

机构：

[1] Department of Obstetrics and Gynaecology, City Hospital, Nottingham, Hucknall Road

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1979年 / 86卷 / 07期

关键词：

D O I：

10.1111/j.1471-0528.1979.tb10810.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The plasma sex hormone binding globulin (SHBG) capacity has been measured in 52 normal women, 11 women on various oral contraceptives containing 50 μg of ethinyl oestradiol and 11 women on oral contraceptives containing less than 35 μg of ethinyl oestradiol. The results show that women on oral contraceptives containing 50 μg of ethinyl oestradiol have a significantly raised SHBG capacity (p < 0·005) whereas those patients on oral contraceptives containing 35 μg or less of ethinyl oestradiol have SHBG capacities which do not differ significantly from normal ovulating women (p >005). Thus the 35 μg pill interferes less with bound/unbound sex steroid ratios than does the 50 μg pill. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：563 / 567

页数：5