STRUCTURAL ABNORMALITIES IN MURINE LEUKEMIA VIRUSES PRODUCED BY INTERFERON-TREATED CELLS

被引:16
作者
BANDYOPADHYAY, AK
CHANG, EH
LEVY, CC
FRIEDMAN, RM
机构
[1] NCI,DERMATOL BRANCH,BETHESDA,MD 20014
[2] NIAMDD,EXPTL PATHOL LAB,BETHESDA,MD 20014
关键词
D O I
10.1016/S0006-291X(79)80003-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The infectivity of Moloney murine leukemia virus (MMLV) particles derived from interferon-treated mouse TB cells is very low. There is a defective viral protein-protein complex between viral p30 antigen and reverse-transcriptase in MMLV produced by interferon-treated TB cells. This defect may account in part for the decreased infectivity of these virus particles. © 1979 Academic Press, Inc. All rights of reproduction in any form reserved.
引用
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页码:983 / 988
页数:6
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