ACCUMULATION OF MYOSIN, ACTIN, TROPOMYOSIN, AND ALPHA-ACTININ IN CULTURED MUSCLE-CELLS

被引:20
作者
ALLEN, RE [1 ]
STROMER, MH [1 ]
GOLL, DE [1 ]
ROBSON, RM [1 ]
机构
[1] IOWA STATE UNIV SCI & TECHNOL, IOWA AGR & HOME ECON EXPT STN, MUSCLE BIOL GRP, AMES, IA 50011 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0012-1606(79)90318-X
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In an effort to understand the conditions that promote the assembly of myofibrillar proteins in muscle cells, the temporal sequence of accumulation of four myofibrillar proteins, actin, myosin, tropomyosin, and α-actinin, was monitored during the period of de novo assembly of myofibrils in differentiating muscle cells. Isotope dilution experiments indicated that all four proteins were accumulated simultaneously. Therefore, assembly of myofibrils may be occurring in the presence of a full complement of myofibrillar proteins. © 1979.
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页码:655 / 660
页数:6
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