DESIGN AND SYNTHESIS OF NEW FLUOROGENIC HIV PROTEASE SUBSTRATES BASED ON RESONANCE ENERGY-TRANSFER

被引：70

作者：

WANG, GT ^{[1
]}

MATAYOSHI, E ^{[1
]}

HUFFAKER, HJ ^{[1
]}

KRAFFT, GA ^{[1
]}

机构：

[1] ABBOTT LABS,N CHICAGO,IL 60064

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(00)97099-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The design and synthesis of new fluorogenic substrate probes for HIV protease based on resonance energy transfer arc described. These substrates permit sensitive, continuous measurement of HIV protease activity. © 1990.

引用

页码：6493 / 6496

页数：4

共 15 条

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